The main flight option for the route Tashkent – Karaganda (round-trip) involves a layover. Prices start at 27 615c̲.
The lowest prices for flights with layovers are offered by Air Astana with a layover in Almaty. Tickets start at 12 286c̲.
Aviasales.kg suggests buying tickets from Tashkent Karaganda in advance in order to choose the conditions for your flight that best suit your preferences and budget.